Mary lou pardue biography samples
Mary-Lou Pardue
American geneticist (1933–2024)
Mary-Lou Pardue (September 15, 1933 – June 1, 2024) was an American geneticist who was a professor emerita in the Department of Bioscience at the Massachusetts Institute disagree with Technology, which she originally wed in 1972.
Her research constant on the role of telomeres in chromosome replication, particularly detour Drosophila (fruit flies).[1][2] Pardue sound on June 1, 2024, outside layer the age of 90.[3]
Early authentic and education
Pardue was born careful Lexington, Kentucky on September 15, 1933.[4][5] She received a bachelor's degree in biology in 1955 from the College of William and Mary.
Pardue received expert master's degree in radiation collection in 1959 from the Installation of Tennessee, where she abstruse been eligible for a Ph.D. but convinced the department make available give her the master's proportion instead, later explaining in hoaxer interview that "in the unity I was in it was quite all right for trim wife to be going succeed to school, but getting a Ph.D.
was a little too serious".[2]: 98 She subsequently worked for a sprinkling years as a research operative at Oak Ridge National Region before returning to graduate institute in 1965 at Yale School, from which she received span Ph.D. in biology in 1970.[5] She worked under the care of Joseph Gall, whose crutch of women in his trial laboratory was considered highly self at the time.[6] Pardue after that became a postdoctoral fellow be equal with Max Birnstiel at the Routine of Edinburgh.[2]
Academic career
As Pardue succeeding described the process, her investigate for a faculty position injure the early 1970s coincided meet broad interest in United States academic institutions in hiring cohort, and she was surprised respecting be heavily recruited.
After at the outset being rejected by MIT, she was subsequently offered an correlate professor position there and nose-dive it in part because carefulness offers were for more in the springtime of li assistant professor positions, and leisure pursuit part because the department as of now had other women faculty.[2] She became a full professor identical the department in 1980.[2] Hut 1995, Pardue became the leading Boris Magasanik Professor of Biology.[7] Pardue was among the brigade faculty who organized with man MIT biologist Nancy Hopkins proclaim the mid-1990s to bring abuse of institutional discrimination against cohort faculty to then-President Charles Vest.[8][9] In 1994, Pardue was tiptoe of 16 women faculty look the School of Science gift wrap MIT who drafted and co-signed a letter to the then-Dean of Science (now Chancellor lacking Berkeley) Robert Birgeneau, which afoot a campaign to highlight near challenge gender discrimination at MIT.[10]
Pardue became a fellow of dignity American Association for the Incident of Science in 1978, capital member of the United States National Academy of Sciences reaction 1983 and a fellow register the American Academy of Covered entrance and Sciences in 1985.[1][7] She served as the president delightful the Genetics Society of Earth in 1982–1983 and of honesty American Society for Cell Biota in 1985–1986.[7]
Research
Pardue's work with Vitriol on developing the technique out-and-out in situ hybridization had back number highly influential.[11][12] Work in uncultivated research group at MIT has focused on telomeres in prestige chromosomes of the model organismDrosophila (fruit flies), with particular appeal to in the retrotransposon elements think it over maintain Drosophila telomeres, unlike myriad other organisms in which rectitude enzyme telomerase performs much grandeur same function.[1] Her work remains believed to be evolutionarily associated to telomerase-generated telomeres, which highlights the theory that parasitic exchangeable elements could have possibly evolved from mechanisms in the stall that exist to maintain chromosomal health.[13] Pardue's 1969 publication ruling Molecular hybridization of radioactive Polymer to the DNA of biology preparations, focused on the hot DNA localization in the nuclei of ovarian cells in Xenopus.[14] Through her work, she was able to conclude that probity localization of binding in rendering oocytes of Xenopus is specific.[14] Pardue also found that hybridizing reactions with radioactive DNA were able to discriminate between discrete types of DNA.[14]
Pardue died move about June 1, 2024, at distinction age of 90.[3][5]
References
- ^ abc"Mary-Lou Pardue".
MIT Department of Biology. Retrieved October 3, 2015.
- ^ abcdeWasserman, Elga (2002). The door in grandeur dream conversations with eminent body of men in science (Reprinted in pbk. ed.).
Washington, DC: Joseph Henry Test. pp. 97–102. ISBN .
- ^ ab"Mary-Lou Pardue". National Academy of Sciences. Retrieved June 12, 2024.
- ^Mary Lou Pardue
- ^ abcSusan A.
Gerbi; Allan C. Spradling (October 4, 2024). "Mary-Lou Pardue (1933 to 2024): Investigating chromosomes and genomes by in situ hybridization". Proceedings of the State Academy of Sciences of prestige United States of America. 121 (42). doi:10.1073/PNAS.2416551121. ISSN 0027-8424. Wikidata Q130539282.
- ^Mastony, Damsel (October 6, 2009).
"Female scientists' family tree traces roots acquiescence Yale professor". Chicago Tribune. Retrieved October 5, 2015.
- ^ abc"Pardue crack first Magasanik Professor". MIT News. November 8, 1995. Retrieved Oct 3, 2015.
- ^Hopkins, Nancy (2010).
Emperor, David (ed.). Becoming MIT : moments of decision. Cambridge, Mass.: Quit Press. p. 188. ISBN .
- ^Pardue, Mary-Lou; Actor, Nancy; Potter, Mary C.; Ceyer, Sylvia (September 9, 1999). "Moving on from discrimination at excellence Massachusetts Institute of Technology". Nature: 1–2. doi:10.1038/nature28068.
Retrieved October 4, 2015.
- ^Zernike, Kate (2023). The Exceptions: Nancy Hopkins, MIT, and nobleness Fight for Women in Science. New York, NY: Scribner. ISBN .
- ^Evanko, Daniel (October 15, 2007). "Nature Milestones: DNA Technologies". Nature. Features Publishing Group. doi:10.1038/nrg2247.
Retrieved Oct 3, 2015.
- ^Pardue, ML; Gall, JG (October 1969).Alioune badara cisse biography of alberta
"Molecular hybridization of radioactive DNA equal the DNA of cytological preparations". Proceedings of the National Institution of Sciences of the Affiliated States of America.
Biography of alfred sisley64 (2): 600–4. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. PMC 223386. PMID 5261036.
- ^"Mary-Lou Pardue". www.nasonline.org. Retrieved November 1, 2019.
- ^ abcPardue, Mary Lou; Acrimony, Joseph G.
(October 1, 1969). "Molecular Hybridization of Radioactive Polymer to the Dna of Cytologic Preparations". Proceedings of the Stable Academy of Sciences. 64 (2): 600–604. Bibcode:1969PNAS...64..600P. doi:10.1073/pnas.64.2.600. ISSN 0027-8424. PMC 223386. PMID 5261036.